Dr. Mitchell Golbus received his B.S. in Psychology from the Illinois Institute of Technology and his M.D. from the University of Illinois School of Medicine. He is presently Professor Emeritus of the Obstetrics and Pediatrics Departments at University of California at San Francisco and Director of Scientific and Clinical Affairs for Applied Imaging Corp. He has been Professor of the Obstetrics and Pediatrics Departments for 25 years. Golbus is certified by the U.S. Obstetrics and Gynecology and Medical Genetics and Israel Obstetrics and Gynecology and Medical Genetics Boards.
Golbus was one of the early forerunners of fetoscopy and chorionic villus sampling (CVS). Working in conjunction with Yale geneticists Maurice Mahoney and Perinatologist John C Hobbins they published very early papers on the prenatal diagnosis of Haemophilia A and Duchenne's muscular dystrophy. Among other genetic "innovations", Golbus discovered a method for recognizing embryonic hemoglobin-containing fetal cells taken from a maternal blood sample. The method allows for the isolation and recognition of fetal nucleated erythrocytes or erythroblasts from a blood sample of a pregnant woman. It is composed of two elements: treating the blood sample with an antibody, or antibody fragment, that will bind specifically to fetal cells; and identifying the bound cells as fetal nucleated erythrocytes or erythroblasts. The method bears a US patent.
A member of various professional organizations, Golbus has served on numerous national committees including the American College of Obstetricians and Gynecologists and the American Society of Human Genetics. He has served as Perinatologist at the Fetus Treatment Center at the University of San Francisco, one of the most advanced centers for in-ultero fetal surgery. His public service includes the California Birth Defects Monitoring Program and the California State Department of Health Services.
Golbus has published widely in his field. He presently sits on the Editorial Boards of Prenatal Diagnosis, Israel Journal of Obstetrics and Gynecology, Obstetrical and Gynecologic Survey, and the Journal of Maternal-Fetal Medicine.